Retinyl Acetate is a naturally-occurring fatty acid ester form of retinol (vitamin A). Vitamin A has exhibited potential antineoplastic and chemopreventive activities. This is exhibited through the binding to and activation of retinoid receptors, inducing cell differentiation and decreasing cell proliferation.
This agent also inhibits carcinogen-induced neoplastic transformation in some cancer cell types and exhibits immunomodulatory properties.
Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea
Moon, Richard C.; Grubbs, Clinton J.; Sporn, Michael B.; Goodman, Dawn G. (1977). "Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea". Nature. 267 (5612): 620–1. doi:10.1038/267620a0. PMID 876383