Madecassoside

CAS Number: 34540-22-2   |   Synonyms: Asiaticoside A; (2α, 3β, 4α,6β)-2,3,6,23-Tetrahydroxylurs-12-en-28-oic Acid; O-6-deoxy-α-L-manno-pyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl Ester; Tiger grass; Gotu Kola; Centella Asiatica


Product InfoStructurePhysical PropertiesProduct DataTransportation DataSpecification Sheet

PRODUCT INFORMATION

Product Name:
Madecassoside

Product Description:
Nature’s Skin Recovery Present Madecassoside is extracted from Centella Asiatica (Gotu Kola) which has traditionally been used as a herbal remedy for a variety of diseases. Now, scientifically referenced journals indicate madecassoside provides active ingredient benefits pertaining to increasing collagen synthesis and reduction of inflammation related to P. Acnes in cosmetic formulations.

Quality Grade:
non-GMP

Usage Unit:
KG

Source:
-

Synonyms:
Asiaticoside A; (2α, 3β, 4α,6β)-2,3,6,23-Tetrahydroxylurs-12-en-28-oic Acid; O-6-deoxy-α-L-manno-pyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl Ester; Tiger grass; Gotu Kola; Centella Asiatica

STRUCTURE

SKU: 34540222 Category:
PHYSICAL PROPERTIES
S.NOPropertyValueReference
REFERENCES
S.NOTitleSourceNotesAuthor(s)DOI
1Propionibacterium acnes related anti-inflammation and skin hydration activities of madecassoside, a pentacyclic triterpene saponin from Centella asiaticaBioscience, Biotechnology, and Biochemistry- Madecassoside inhibited pro-inflammatory cytokines stimulated by P. Acnes - Madecassoside upregulated hydration components leading to enhanced skin barrier function and less moisture lossXueqing Shen, Miaomiao Guo, Haiyuan Yu, Dan Liu, Zhi Lu & Yanhua Lu10.1080/09168451.2018.1547627
2Centella asiatica in Dermatology: An OverviewPhytotherapy ResearchLiterature review of C. Asiatica uses with relation to madecassoside: - Madecassoside/ Asiaticoside mixture was found, in vitro, to increase type I collagen by 25 - 30% with potential use for wound healing - Madecassoside was found to increase antioxidative activities and enhance collagen synthesis (increased glutathione and hydroxyproline which are key indicators) in vivo.Wiesława Bylka, Paulina Znajdek-Awiżeń, Elżbieta Studzińska-Sroka, Aleksandra Dańczak-Pazdrowska and Małgorzata Brzezińska10.1002/ptr.5110
PRODUCT DATA

Molecular Formula:
C48H78O20

Molecular Weight:
975.12

EC Number:
252-076-1

Functional Categories:

Purity Value:
-

Storage Temperature:
-

INCI Name:
MADECASSOSIDE

TRANSPORTATION DATA

UN Class:
-

UN Packing Group:
-

Harmonized Tariff Number:
2938.90.90

UN Number:
-

Use Level:
-

China Registered:
Yes

SPECIFICATION SHEET

Rev No:
1

SPECIFICATION DATA

S.NOGroupingAnalytical TestSpecification
1-AppearanceWhite powder
2-TLCStandard
3-LOD< 3%
4Heavy metals-<20 ppm
5--Pb< 0.5 ppm
6--As< 0.5 ppm
7--Hg< 0.05 ppm
8--Cd< 0.3 ppm
9--Cu< 5 ppm
10-Sulfated Ash< 1.0%
11-Assay (HPLC)> 90%
12Microbiological Specifications--
13-Total Aerobic (CFU/g)< 1000 cfu/g
14-E. ColiNegative
15-SalmonellaNegative
16-Mold and Yeast (CFU/g)< 100 cfu/g
17Manufacturing and Regulatory Data--
18-Date of Manufacture-
19-Retest Date2 Years

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