Madecassoside
CAS Number: 34540-22-2 | Synonyms: Asiaticoside A; (2α, 3β, 4α,6β)-2,3,6,23-Tetrahydroxylurs-12-en-28-oic Acid; O-6-deoxy-α-L-manno-pyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl Ester; Tiger grass; Gotu Kola; Centella Asiatica
Product InfoStructurePhysical PropertiesProduct DataTransportation DataSpecification Sheet
PRODUCT INFORMATION
Product Name:
Madecassoside
Product Description:
Nature’s Skin Recovery Present
Madecassoside is extracted from Centella Asiatica (Gotu Kola) which has traditionally been used as a herbal remedy for a variety of diseases. Now, scientifically referenced journals indicate madecassoside provides active ingredient benefits pertaining to increasing collagen synthesis and reduction of inflammation related to P. Acnes in cosmetic formulations.
Quality Grade:
non-GMP
Usage Unit:
KG
Source:
-
Synonyms:
Asiaticoside A; (2α, 3β, 4α,6β)-2,3,6,23-Tetrahydroxylurs-12-en-28-oic Acid; O-6-deoxy-α-L-manno-pyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl Ester; Tiger grass; Gotu Kola; Centella Asiatica
REFERENCES
| S.NO | Title | Source | Notes | Author(s) | DOI |
|---|---|---|---|---|---|
| 1 | Propionibacterium acnes related anti-inflammation and skin hydration activities of madecassoside, a pentacyclic triterpene saponin from Centella asiatica | Bioscience, Biotechnology, and Biochemistry | - Madecassoside inhibited pro-inflammatory cytokines stimulated by P. Acnes - Madecassoside upregulated hydration components leading to enhanced skin barrier function and less moisture loss | Xueqing Shen, Miaomiao Guo, Haiyuan Yu, Dan Liu, Zhi Lu & Yanhua Lu | 10.1080/09168451.2018.1547627 |
| 2 | Centella asiatica in Dermatology: An Overview | Phytotherapy Research | Literature review of C. Asiatica uses with relation to madecassoside: - Madecassoside/ Asiaticoside mixture was found, in vitro, to increase type I collagen by 25 - 30% with potential use for wound healing - Madecassoside was found to increase antioxidative activities and enhance collagen synthesis (increased glutathione and hydroxyproline which are key indicators) in vivo. | Wiesława Bylka, Paulina Znajdek-Awiżeń, Elżbieta Studzińska-Sroka, Aleksandra Dańczak-Pazdrowska and Małgorzata Brzezińska | 10.1002/ptr.5110 |
PRODUCT DATA
Molecular Formula:
C48H78O20
Molecular Weight:
975.12
EC Number:
252-076-1
Purity Value:
-
Storage Temperature:
-
INCI Name:
MADECASSOSIDE
TRANSPORTATION DATA
UN Class:
-
UN Packing Group:
-
Harmonized Tariff Number:
2938.90.90
UN Number:
-
Use Level:
-
China Registered:
Yes
SPECIFICATION SHEET
Rev No:
1
SPECIFICATION DATA
| S.NO | Grouping | Analytical Test | Specification |
|---|---|---|---|
| 1 | - | Appearance | White powder |
| 2 | - | TLC | Standard |
| 3 | - | LOD | < 3% |
| 4 | Heavy metals | - | <20 ppm |
| 5 | - | -Pb | < 0.5 ppm |
| 6 | - | -As | < 0.5 ppm |
| 7 | - | -Hg | < 0.05 ppm |
| 8 | - | -Cd | < 0.3 ppm |
| 9 | - | -Cu | < 5 ppm |
| 10 | - | Sulfated Ash | < 1.0% |
| 11 | - | Assay (HPLC) | > 90% |
| 12 | Microbiological Specifications | - | - |
| 13 | - | Total Aerobic (CFU/g) | < 1000 cfu/g |
| 14 | - | E. Coli | Negative |
| 15 | - | Salmonella | Negative |
| 16 | - | Mold and Yeast (CFU/g) | < 100 cfu/g |
| 17 | Manufacturing and Regulatory Data | - | - |
| 18 | - | Date of Manufacture | - |
| 19 | - | Retest Date | 2 Years |