Product InfoStructurePhysical PropertiesProduct DataTransportation DataSpecification Sheet
Forskolin – Give your hair a renewed appearance
Forksolin is a diterpenoid extracted from Coleus Forskohlii. Scientific literature references indicate that forskolin promotes melanization and can protect against skin UV-damage by increased eumelanin production and epidermal thickening.
|1||In Vitro Skin Diffusion Study of Pure Forskolin versus a Forskolin-Containing Plectranthus barbatus Root Extract||J. Nat. Prod.||- Forskolin stimulates adenyl cyclase to promote cAMP accumulation
- Forskolin and extract promoted melanization in murine model with humanized skin and mutant MC1R. Protected eumelanin was produced
- In vitro study comparing forskolin vs. extract showed higher skin permeation for extract||Jing Chen, Dana C. Hammell, Malinda Spry‡, John A. D’Orazio‡, and Audra L. Stinchcomb||10.1021/np800541k|
|2||Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation||Exp Dermatol||- Forskolin induced skin darkening by accumulation of melanin in epidermis. Epidermal was found to be thicker than controls (hypothesized from increased epidermal keratinocytes of hypertrophy of existing cells)
- Epidermal thickening associated with decrease in UVA and UVB penetration through the skin.||Timothy L Scott, Perry A Christian, Melissa V Kesler, Kevin M Donohue, Brent Shelton, Kazumasa Wakamatsu, Shosuke Ito, John D'Orazio||10.1111/exd.12012|
Coleus Forskohlii Root Extract (proposed)
Harmonized Tariff Number:
Looking for a custom solution? Get a quote today!