Wilshire Technologies provide effective custom synthesis solutions tailored to meet customers’ needs as well as FTE services. Our synthetic laboratories operate from a well-equipped world-wide CMO facilities. Our scientists are skilled in design and custom synthesis of complex multi-step reaction schemes. We handle from mg to Kg scale and are able to transfer technology to our bulk manufacturing plant.  

We specialize in the following chemistries and custom synthesis services:

  • Acylation
  • Alkylation
  • Amidation
  • Chlorination – POCl3, SOCl2, PCl3
  • Condensation
  • Cyanation
  • Diazonium chemistry
  • Diels-Alder reaction
  • Esterification
  • Friedel-Crafts
  • Grignard chemistry
  • Halogenation
  • Heterocyclic synthesis
  • Metal Hydride Reductions – NaBH4, LAH, Vitride
  • Nitration
  • Natural product synthesis
  • Oxidation
  • Phosgenation
  • Reduction

Our state-of-the-art synthetic labs are equipped with modern preparative and analytical tools:

  • Size exclusion chromatography (SEC)
  • Preparative HPLC
  • Rotavapors and Freeze Dryers
  • Nuclear magnetic resonance (NMR)
  • Liquid Chromatography–Mass Spectrometry (LC-MS)
  • Ultra-Performance Liquid Chromatography (UPLC)
  • Ion Chromatography (IC) system
  • Gas chromatography (GC)
  • Inductively Coupled Plasma (ICP) for metal ion analysis
  • Polarimeter for optical rotation measurements